Research from universities around the world has shown that Juice Plus+® delivers key phytonutrients that are absorbed by the body
Published studies conducted by independent researchers from around the world have shown that various phytonutrients in Juice Plus+ are bioavailable.
Kings College, London
Leeds et al. Journal of Human Nutrition and Dietetics, 2000
Study summary and findings:
This study was designed to determine if consumption of Juice Plus+ Orchard Blend and Juice Plus+ Garden Blend capsules would result in increased blood concentrations of antioxidants. This was a study of sixteen healthy British participants (18-52 years of age). These subjects were divided into two groups of eight with one group assigned to take two Juice Plus+ Orchard Blend capsules and the other group to take two Juice Plus+ Garden Blend capsules daily for one week. All the study participants followed a low beta-carotene diet, starting four days before the study began and throughout the investigation. Fasting blood samples were analyzed to determine levels of vitamin C, vitamin E (alpha-tocopherol), beta-carotene, and malondialdehyde (an indicator of lipid peroxidation). Concentrations of both vitamin C and beta-carotene rose significantly after daily consumption of both the Juice Plus+ Orchard Blend and Juice Plus+ Garden Blend capsules. The levels of plasma malondialdehyde fell significantly in both groups.
Complete Article: Journal of Human Nutrition and Dietetics, 2000; 13 (1): 21-27
Tokyo Women's Medical University
Kawashima et al. Asia Pacific Journal of Clinical Nutrition, 2007
Study summary and findings:
This study compared the effect of Juice Plus+ or placebo on plasma levels of various micronutrients. This investigation had a randomized double-blind, placebo-controlled design and included 60 healthy Japanese men and women, with an average age of 27.8 years. About half of these study subjects were smokers. The study subjects took either Juice Plus+ or a placebo for 28 days. Concentrations of the carotenoids beta-carotene and lycopene, vitamin E and folate significantly increased while homocysteine and lipid peroxides were significantly decreased in the Juice Plus+ group over this study period.
Article abstract: Asia Pacific Journal of Clinical Nutrition, 2007; 16 (3): 411-421
Medical University of Vienna
Kiefer et. al. Journal of the American College of Nutrition, 2004
Study summary and findings:
This study compared the effect of Juice Plus+ or placebo on plasma levels of various micronutrients, and on a urinary marker of oxidative stress while monitoring dietary habits of the study subjects. This investigation had a double-blind, placebo-controlled randomized crossover of 59 healthy Austrian men and women, aged 40-60 years. The study subjects were divided into two groups, who took either Juice Plus+ or a placebo first for a total of 14 weeks (for example, seven weeks on Juice Plus+ , seven weeks on placebo). Blood concentrations of beta-carotene, vitamin C, vitamin E, and folate were measured at baseline and at the end of each crossover phase (week 7 and 14). Quantitation of the urinary marker and retrospective food frequency questionnaire responses were also determined at these times. Significant increases in beta-carotene, vitamin C, vitamin E, and folate were detected after the Juice Plus+ phase but not after the placebo phase. No significant changes were observed in the urinary measure. All participants fell short of the recommended goal of five fruit and vegetable servings at each time point in the study.
Complete Article: Journal of the American College of Nutrition, 2004; 23 (3): 205-211
University of Sydney, Australia
Samman et al. Journal of Nutrition, 2003
Study summary and findings:
This study measured the effect Juice Plus+ on plasma levels of selected vitamins, recognized coronary heart disease (CHD) risk factors, and general antioxidant status. Thirty- two healthy Australian men participated in this double-blind, placebo-controlled randomized crossover trial, consisting of two intervention periods of six weeks each, separated by a three week wash-out phase. During the intervention periods, subjects took either Juice Plus+ or placebo. Blood samples for nutrient analysis of and plasma antioxidant capacity were obtained at baseline, and again at the end of the third and sixth week for each intervention period. Plasma folate, vitamin C, alpha-tocopherol (vitamin E), retinol, and beta-carotene all increased significantly during the Juice Plus+ intervention period compared to placebo period. There was a trend (p = 0.065) for increased plasma antioxidant capacity, and a significant reduction in homocysteine during the Juice Plus+ intervention period.
Complete Article: Journal of Nutrition, 2003; 133 (7): 2188-2193
Georgetown/UCLA
Wise et al. International Journal of Food Sciences and Nutrition 2009; 60: S65-75
Study summary and findings:
This study demonstrated bioavailability after 28 days, specifically of beta-carotene and vitamin E (alpha-tocopherol), in an overweight population of 92 middle aged and otherwise healthy men and women given Juice Plus+ Orchard and Garden Blends compared to placebo capsules.
Complete Article: International Journal of Food Science and Nutrition, 2009; 60: S65-75
Brigham Young University
Smith et al. Nutrition Research, 1999
Study summary and findings:
This research determined the effect of Juice Plus+ on phytonutrients status and on lymphocyte DNA structural integrity, as measured by resistance to in vitro damage. Twenty healthy men and women (over sixty years of age) participated in this study. Subjects consumed Juice Plus+ capsules daily for 80 days. Blood for antioxidant analysis and to obtain lymphocytes (white blood cells) was collected at baseline and day 80. This study used the comet assay, an in vitro technique used to measure DNA damage in nuclei of the lymphocytes, measured by the length of the tail moment. This study found a significant decrease (shorter tail moment) in susceptibility to DNA damage after consumption of Juice Plus+ for 80 days compared with baseline values. A significant increase over baseline value was observed for the phytonutrients beta-carotene and alpha-carotene.
Complete Article: Nutrition Research, 1999; 19 (10): 1507-1518
University of Arizona
Inserra et al. Integrative Medicine, 1999
Study summary and findings:
Daily consumption of Juice Plus+ effectively increased plasma levels of important antioxidant nutrients and led to an improvement in selected markers for immune function in this elderly population. The aim of the study was to investigate the effect of Juice Plus+ on immune function and serum antioxidant concentration in elderly people. Forty-six healthy, elderly (age sixty or older) adults completed this study. All subjects consumed Juice Plus+ daily for 80 days. Blood samples were taken at baseline, and again at study day 40 and day 80. Levels of select phytonutrients (lutein/zeaxanthin, alpha-carotene, beta-carotene, lycopene and alpha-tocopherol) increased significantly and several measures of immune function improved compared to baseline values after consumption of Juice Plus+ capsules.
Complete Article: Integrative Medicine, 1999; 2 (1): 3-10
University of Florida
Nantz et al. Journal of Nutrition, 2006
Study summary and findings:
Daily consumption of Juice Plus+ for eleven weeks effectively increased plasma levels of important antioxidant nutrients and led to an improvement in a marker of immune function and reduction of DNA damage in law school students.
This research determined the effect of Juice Plus+ on phytonutrient status, on markers of immune function, and on lymphocyte (white blood cell) DNA structural integrity as measured by resistance to damage. Fifty-nine (59) healthy law school students participated in this study. Subjects consumed Juice Plus+ capsules daily for 77 days (eleven weeks). Blood for antioxidant analysis and to obtain lymphocytes was collected at baseline, day 35 and day 77. This study found an increase in a specific type of T cell (gamma delta) which plays a role in protecting the body from microbes associated with infectious illness. In addition, a significant decrease over baseline values in susceptibility to DNA damage after consumption of Juice Plus+ at both 35 and 77 days and a significant increase over baseline values for the phytonutrients beta-carotene, lutein, lycopene, and vitamin C were also observed.
Complete Article: Journal of Nutrition, 2006; 136: 2606-2610
University of Texas
Morin et al. Current Therapeutic Research, 1996
Study summary and findings:
Daily use of Juice Plus+ for 28 days increased plasma levels of select antioxidants, proving bioavailability of these phytonutrients from Juice Plus+ capsules. This pilot study also found daily use of Juice Plus+ resulted in reduction in serum lipid peroxides, a biomarker of oxidation.
This study determined the efficacy of Juice Plus+ to increase plasma values of select carotenoids and tocopherol, and to decrease a functional measure of oxidative status. This pilot investigation was conducted on fifteen healthy American male and female subjects between 18-53 years of age who took Juice Plus+ capsules in addition to their regular diet for 28 days. Blood samples were collected 1-4 days prior to introducing the capsules into the regular diet; and again at weekly (study day 7, 14 and 28) intervals during the study period. Plasma levels of a number of antioxidants and serum lipid peroxides were analyzed at each of these time intervals. Compared to baseline values, these results showed an increase in plasma alpha-tocopherol (Vitamin E), beta-carotene, and related carotenoids such as lycopene, zeaxanthin/lutein and alpha-carotene along with a decrease in lipid peroxides, following daily use of Juice Plus+ for 28 days.
Complete Article: Current Therapeutic Research, 1996; 57 (6): 445-461